About the cover Dec. 2017; Volume 36 Issue 12 |
1, On December 19, 1978, cisplatin, the "penicillin of cancer drugs", was approved for use in testicular and ovarian cancers by the U.S. Food and Drug Administration. 2, In December 1942, nitrogen mustards started to be used as an effective treatment for cancer for the treatment of lymphoma in human clinical trials, which is the beginning of the modern era of cancer chemotherapy. |
Research Highlight
Chromatin remodeling factor lymphoid-specific helicase inhibits ferroptosis through lipid metabolic genes in lung cancer progression
Yiqun Jiang, Yuchen He, Shuang Liu and Yongguang Tao
[ Abstract 217] [ PDF Full-text 225] [ HTML Full-text 160]   Epub: 10/16/2017 doi: 10.1186/s40880-017-0248-x
Editorial
Awakening immunity against cancer: a 2017 primer for clinicians
Amit Jain, Qing Zhang and Han-Chong Toh
[ Abstract 716] [ PDF Full-text 443] [ HTML Full-text 306]   Epub: 8/20/2017 doi: 10.1186/s40880-017-0233-4
Original Article
Famitinib versus placebo in the treatment of refractory metastatic colorectal cancer: a multicenter, randomized, double-blinded, placebo-controlled, phase II clinical trial
Rui-Hua Xu, Lin Shen, Ke-Ming Wang, Gang Wu, Chun-Mei Shi, Ke-Feng Ding, Li-Zhu Lin, Jin-Wan Wang, Jian-Ping Xiong, Chang-Ping Wu, Jin Li, Yun-Peng Liu, Dong Wang, Yi Ba, Jue-Ping Feng, Yu-Xian Bai, Jing-Wang Bi, Li-Wen Ma, Jian Lei, Qing Yang and Hao Yu
[ Abstract 613] [ PDF Full-text 237] [ HTML Full-text 157]   Epub: 12/22/2017 doi: 10.1186/s40880-017-0263-y
Nasopharyngeal carcinoma incidence and mortality in China, 2013
Kuang-Rong Wei, Rong-Shou Zheng, Si-Wei Zhang, Zhi-Heng Liang, Zhu-Ming Li and Wan-Qing Chen
[ Abstract 247] [ PDF Full-text 424] [ HTML Full-text 210]   Epub: 11/10/2017 doi: 10.1186/s40880-017-0257-9
Expression of voltage-gated sodium channel Nav1.5 in non-metastatic colon cancer and its associations with estrogen receptor (ER)-β expression and clinical outcomes
Jianhong Peng, Qingjian Ou, Xiaojun Wu, Rongxin Zhang, Qian Zhao, Wu Jiang, Zhenhai Lu, Desen Wan, Zhizhong Pan and Yujing Fang
[ Abstract 210] [ PDF Full-text 243] [ HTML Full-text 202]   Epub: 11/10/2017 doi: 10.1186/s40880-017-0253-0
Hepatic artery infusion chemotherapy using mFOLFOX versus transarterial chemoembolization for massive unresectable hepatocellular carcinoma: a prospective non-randomized study
Min-Ke He, Yong Le, Qi-Jiong Li, Zi-Shan Yu, Shao-Hua Li, Wei Wei, Rong-Ping Guo and Ming Shi
[ Abstract 240] [ PDF Full-text 318] [ HTML Full-text 199]   Epub: 10/23/2017 doi: 10.1186/s40880-017-0251-2
Systematic analyses of glutamine and glutamate metabolisms across different cancer types
Yuan Tian, Wei Du, Sha Cao, Yue Wu, Ning Dong, Yan Wang and Ying Xu
[ Abstract 581] [ PDF Full-text 246] [ HTML Full-text 150]   Epub: 11/10/2017 doi: 10.1186/s40880-017-0255-y
Synthetic lethal short hairpin RNA screening reveals that ring finger protein 183 confers resistance to trametinib in colorectal cancer cells
Rong Geng, Xin Tan, Zhixiang Zuo, Jiangxue Wu, Zhizhong Pan, Wei Shi, Ranyi Liu, Chen Yao, Gaoyuan Wang, Jiaxin Lin, Lin Qiu, Wenlin Huang and Shuai Chen
[ Abstract 300] [ PDF Full-text 324] [ HTML Full-text 311]   Epub: 7/31/2017 doi: 10.1186/s40880-017-0228-1
Prognostic values of the integrated model incorporating the volume of metastatic regional cervical lymph node and pretreatment serum Epstein–Barr virus DNA copy number in predicting distant metastasis in patients with N1 nasopharyngeal carcinoma
Ji-Jin Yao, Guan-Qun Zhou, Ya-Qin Wang, Si-Yang Wang, Wang-Jian Zhang, Ya-Nan Jin, Fan Zhang, Li Li, Li-Zhi Liu, Zhi-Bin Cheng, Jun Ma, Zhen-Yu Qi and Ying Sun
[ Abstract 185] [ PDF Full-text 168] [ HTML Full-text 119]   Epub: 12/29/2017 doi: 10.1186/s40880-017-0264-x
Conditional survival in patients with gallbladder cancer
Yi-Jun Kim and Kyubo Kim
[ Abstract 185] [ PDF Full-text 202] [ HTML Full-text 150]   Epub: 11/10/2017 doi: 10.1186/s40880-017-0252-1
Significant value of 18F-FDG-PET/CT in diagnosing small cervical lymph node metastases in patients with nasopharyngeal carcinoma treated with intensity-modulated radiotherapy
Hao Peng, Lei Chen, Ling-Long Tang, Wen-Fei Li, Yan-Ping Mao, Rui Guo, Yuan Zhang, Li-Zhi Liu, Li Tian, Xu Zhang, Xiao-Ping Lin, Ying Guo, Ying Sun and Jun Ma
[ Abstract 198] [ PDF Full-text 213] [ HTML Full-text 161]   Epub: 12/19/2017 doi: 10.1186/s40880-017-0265-9
Expression and clinical value of programmed cell death-ligand 1 (PD-L1) in diffuse large B cell lymphoma: a retrospective study
Li-Yang Hu, Xiao-Lu Xu, Hui-Lan Rao, Jie Chen, Ren-Chun Lai, Hui-Qiang Huang, Wen-Qi Jiang, Tong-Yu Lin, Zhong-Jun Xia and Qing-Qing Cai
[ Abstract 214] [ PDF Full-text 190] [ HTML Full-text 159]   Epub: 12/16/2017 doi: 10.1186/s40880-017-0262-z
Correspondence
Immune evasion might affect survival in laryngeal cancer patients with blood group O
Kadri Altundag
[ Abstract 283] [ PDF Full-text 355] [ HTML Full-text 255]   Epub: 7/14/2017 doi: 10.1186/s40880-017-0223-6